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54gene Completes Initial Phase of the Landmark Nigerian 100K Genome Project

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54gene, the health technology company advancing African genomics research for improved global health outcomes, has through its non-profit initiative, the African Centre for Translational Genetics (ACTG), completed its first consortium-led publication on over 100,000 Nigerians as commissioned in 2020 at its launch.

The Non-Communicable Diseases Genetic Heritage Study (NCD-GHS) consortium has published a paper in the esteemed journal, Nature Genetics, entitled “Promoting the Genomic Revolution in Africa through the Nigerian 100k Genome Project”.

Through 54gene’s ACTG, the consortium operates as a unique public-private partnership involving leading African scientists guided by a team of global genomic leaders as the Scientific Advisory Board to achieve the mission of the ACTG.

The consortium, which is made up of scientists from 54gene, the Nigerian Institute of Medical Research, and the Center for Genomics Research and Innovation at the National Biotechnology Development Agency as well as researchers from multiple academic institutions in Nigeria and London School of Hygiene and Tropical Medicine, is built on a shared vision of positioning African populations to benefit from advances in genomic science.

According to the paper, as of January 2019, approximately 3% of genomic data being used for genome wide association studies (GWAS) came from people of African descent, with this statistic dropping to 1.1% in 2021.

The paper details efforts in building an important resource that could significantly enable African populations to benefit from the global efforts at achieving precision medicine for various diseases.

This has been achieved through the production of a comprehensive catalog of human genetic variation, examining the characteristics of non-communicable diseases (NCDs) in 100,000 adults in Nigeria seeking to understand the genetic basis of the highly prevalent illnesses such as cancers, diabetes, Alzheimer’s, chronic kidney and sickle cell disease, among others.

Non-communicable diseases (NCDs) kill more than 41 million people every year, accounting for 71% of all deaths globally. The prevalence of NCDs is projected to become higher than that of infectious diseases in Africa by 2030.

The study spans the breadth of the Nigerian population with data gathered from the 6 geopolitical zones in the country and sampling from the majority of the more than200 ethnolinguistic groups, with ethically consulted participants being recruited falling under two categories: disease cases recruited from disease specialist clinics, and community cases which are individuals with initially unknown diseases recruited from communities through household surveys.

Dr. Abasi Ene-Obong, 54gene Founder and CEO, said, “Along with our partners, we are proud to be leading the new frontier of African genomics. Precision medicine goes against the one-size-fits-all approach to disease treatment as it is more inclusive, with people treated on their unique genetic makeup.

With more than 200 ethnic groups and 500 different languages, Nigeria has one of the most diverse ethnolinguistic concentrations in the world. This pioneering study from the Nigerian population provides an excellent window into the representation of diversity across Africa.

With recruitment nearly complete and the commencement of data generation and bioinformatics analysis, we are excited at how this study makes the promise of precision medicine more attainable to Nigerians, Africans and the global population.”

Dr. Segun Fatumo, co-lead NCD-GHS and the first author of the landmark paper said, “I am so proud of what NCD-GHS has achieved in only about two years. In our own eyes, 100K genomes of Africa are emerging from more than 300 diverse ethnic groups in Nigeria.

“The current lack of genomic diversity has resulted in significant missed scientific and medical opportunities, but NCD-GHS strategic vision to drive new large-scale studies with rich African genome datasets would  help fill some gaps. I am deeply honoured to be a co-lead of this initiative.

“The NCD-GHS’s public-private partnership with 54gene pioneers a model to increase diversity in genomic studies, including capacity building and plan to develop more genomic leaders in Africa.”

Speaking on the publication of the research paper, Colm O’Dushlaine, Vice President, Genomics and Data Science at 54gene, said, “The 100k project supports 54gene’s core mission to equalize precision medicine, by building rich genomic datasets that will be used to generate powerful insights for the benefit of African, and other global populations.

“African populations are among the most diverse in the world. In the context of genome-wide association scans, more variation – more shots on goal – can help to provide new insights into the etiology of disease and drive novel therapeutic target discovery.

“The broader strategic objectives of the NCD-GHS are far-reaching. They include a focus on the creation of genomics leaders in Africa, efforts to increase the number of skilled African genomics scientists to help drive new studies and discoveries, initiatives that drive progressive health policy and practice, and the promotion of discourse and thought leadership on ethical, legal and social issues in genomics research and precision medicine. All of these are central to 54gene’s mission and values.”

Aminu Yakubu, VP Research Governance and Ethics, said, “Building on the legacy of the H3Africa project, the capacity building objective of the NCD-GHS in the 100K Genome Project is a strategic undertaking that would catalyse the future we envisage – of Africans with the skillset and knowledge, able to lead genomic insights generation and development to address health challenges faced by Africans over the long haul.

“It is a people-facing impact creation initiative that puts the social value of the work we do at the center, facilitated through the African Center for Translational Genetics. The focus of one of the NCD-GHS agendas on governance and ethics was deliberate to ensure that we are aligned with existing country-specific and international best practices.

“Our commitment to also support academic thought leadership on ethics and governance issues in genomics research would allow us to evolve as we learn of better ways to protect the welfare of research participants and ensure fairness in research collaborations.”


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Nigeria among Selected Recipients of $12m VaxSocial Initiative Funding to Boost Vaccine Confidence

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The VaxSocial Initiative, spearheaded by Global Impact in collaboration with the African Health Organisation (AHO) and Gavi, has announced the selection of seven organizations to receive funding totalling  $12 million.

Nigeria among Selected Recipients of $12m VaxSocial Initiative Funding to Boost Vaccine Confidence

This initiative, focused on harnessing the power of social media to bolster vaccine confidence, marks a significant step forward in combating vaccine hesitancy and promoting public health awareness.

The selected organizations from India, Indonesia, and Nigeria were carefully chosen to explore innovative approaches that leverage social media and behavioral science to empower populations to make informed decisions regarding vaccination.

Among the esteemed recipients from Nigeria are as follows:

Nivi and Save the Children,

HelpMum and Behavioral Insights Team, and

Upswell in collaboration with the Behavioral Insights Lab, Silver Lining for the Needy Initiative, and WellaHealth.

The other four recipients include:

GroupM Media India PVT. LTD. (India)

Center for Indonesia’s Strategic Development Initiatives (Indonesia)

Global Health Strategies Emerging Economies PVT. LTD. (Indonesia), and

IPSOS and M&C Saatchi World Services (Evaluator)

This initiative comes at a critical juncture as Nigeria, like many countries globally, grapples with vaccine hesitancy and misinformation. By leveraging the vast reach and influence of social media platforms, these organizations aim to educate and empower communities, particularly in rural and underserved areas, to overcome barriers to vaccination.

Drew Otoo, president of Global Vaccines at MSD, expressed enthusiasm for the initiative’s next phase, highlighting the potential of social media platforms in shaping healthcare decisions. Lu’chen Foster, Senior Director of Social Impact Partnerships at Meta, reiterated Meta’s commitment to supporting global health outcomes through innovative approaches.

Augustin Flory, managing director at Gavi, emphasized the importance of partnerships with the private sector and technology in driving impactful interventions in immunization programs.

The VaxSocial Initiative represents a collaborative effort to bridge the gap between research and implementation, paving the way for evidence-based strategies to enhance vaccine confidence and uptake.

With Nigeria actively participating in this initiative, there is hope for a brighter future where vaccination is embraced as a crucial component of public health, safeguarding communities against preventable diseases.

As these projects unfold, they have the potential to serve as models for scalable and replicable approaches to vaccine advocacy, not only in Nigeria but across the globe.

Through collective efforts and strategic partnerships, we can build a healthier and more resilient world, where every individual has access to life-saving vaccines and the knowledge to make informed healthcare decisions.

 


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Shaping the Future of Solar Energy at Offshore Technology Conference,

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By Okoko Chidozie Christian

[email protected]; 09025179984.

As the world transitions to a more sustainable and low-carbon solar energy future, no other event provides attendees with more diverse conversation focused on the latest developments needed to accelerate the global energy mix, except the Offshore Technology Conference (OTC)

Shaping the Future of Solar Energy at Offshore Technology Conference,

Since 1969, the Offshore Technology Conference, OTC has served as a central hub convening energy professionals from around the world to share ideas and innovations, debate and build consensus around the most pressing topics facing the offshore energy sectors and the globe at large.

The OTC focused on the technologies and innovations needed to continue providing the world’s energy needs while helping to create a cleaner, healthier and more sustainable future for all. It is the only global energy event connecting 31,000+ offshore energy professionals from more than 100 countries to discuss the challenges, solutions and changing environmental landscape of the offshore energy sector.

Across four (4) days, industry-thought leaders, investors, buyers and enterpreneurs will meet in Houston- the energy capital of the world to develop business partnership and learn about the latest advances, challenges and opportunities.

At OTC, there will be access to leading-edge technical information, the industry’s largest equipment exhibition and valuable professional contacts from around the world.

Also, it will provide excellent opportunities for global sharing of technology, expertise, products and practices.

Whether oil and gas, solar, wind, hydrogen, and marine resource, conversations will be centred around innovations that could help shift and drive the world’s energy mix.

Looking at the solar energy issue at the conference, the world will witnessmore paradigm shift towards renewable energy source as a means in combating climate change and reducing dependence on fossil fuels.

Among many options, solar energy has taken the lead to providing a sustainable and plentiful answers to the urgent energy concern of our days.

Also, the world’s energy has increasingly transitioned and focused on using solar energy to fulfil rising energy demands since the sun is an endless supply of clean energy.

Therefore, it is impossible to exaggerate the contributions of solar energy to the global energy shifts.

In terms of generating electricity and alerting the overall energy landscape, solar power has proven to be a game-changer making it possible for nations, communities to lower their carbon footprints, improve energy security, and spur economic growth by using photovoltaic (PV) technology or concentrating solar power(CSP). The unmatched environmental advantage of solar energy is one of its main advantage.

Contrary to the traditional energy source, solar energy emits no greenhouse gaswhile in use; reducing the adverse effect of carbon-dioxide, (CO2) and other air pollutants.
As a result, makes a substantial contribution to the battle against climate change by assisting countries in meeting the Paris Agreement emission reduction goals.

Furthermore, by decentralizing energy generation, solar energy strengthens communities. Homes and businesses may become self-sufficient energy producers by installing solar panels on their rooftops decreasing dependency in centralize power system and fostering energy independence.

Remarkably, the solar business has grown, creating jobs and investments to many countries such as the US, Europe, Japan, Brazil, China to mention but a few. In the US, solar capacity exceeded 135,700MegaWatts as of late 2022, which is enough to power 24million homes according to the Solar Energy Industry Association, SEIA. Typically, solar panel is an attractive investment for homeowners who pay high electricity prices, have roofs with decent sun exposure, want to reduce their environmental impacts and want to pre-pay for a quarter century of power.

Study confirms that there are some misconceptions about solar power, but panels yield excellent result when used in the right application.

Solar panel materials can be recycled and reused between 90% to 97% for other purposes when they break down. This is because solar panels are made up of large amounts of aluminium, copper and glass. These materials can be recycled for other products manufacturing including solar panels-thanks to its modular design.

Solar panels generate electricity for decades without producing carbon emission. By comparison, conventional power plants fired by fossil fuels produces significant emissions during their lifespan and cannot be dismantled as easily as a solar panel.

Do you know that early models of solar panels are still in use today? Solar panels have no moving parts, which means they are not at risk of much mechanical wear.

And, this results in a long service life, and the top solar brands now offer warranties of over 20 years to help maintain your panel over time.

As one of the world energy event that showcase advances in energy, highly interactive experience, inspire progressive leadership thinking and collaborative actions, OTC critically look ahead to the next 100 years of energy; not just what the future in energy technology looks, but also how to increase society’s energy literacy and creates more inclusive, bottom-up energy communities.

 

 

 


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Transcorp Group Delivers Impressive Q1 2024 Performance with Revenue Growth of 173 Percent

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Transnational Corporation Plc (“Transcorp” or the “Group”), Nigeria’s leading, listed conglomerate with investment in the Power, Hospitality, and Energy sectors, has announced impressive Q1 financial results for the period ended March 31, 2024.

Transcorp Group Delivers Impressive Q1 2024 Performance with Revenue Growth of 173 Percent

In its Q1 2024 unaudited results, Transcorp reported significant year-on-year growth, with revenue rising to N88.6 billion from N32.4 billion in 2023, representing a 173% increase.

The impressive results are largely driven by a remarkable 209% year-on-year revenue growth within the power business, highlighting significant strategic progress as part of Transcorp Group’s implementation of its integrated power strategy.

The hospitality business recorded a 68% year-on-year growth in revenue, driven by an increase in occupancy rate from 75% to 82% compared to the previous year.

The results show substantial growth across all financial indicators, reinforcing its market leadership and strategic positioning.

Highlight of Transcorp Group Results:

Q1 2024 Revenue was N88.6 billion, a significant increase of 173%, compared to Q1 2023.

Operating income increased by 479%, from N8.5 billion in Q1 2023 to N49.1 billion in Q1 2024.

Operating expenses saw an increase of 40% year on year to N8.2 billion in Q1 2024, reflecting the impact of inflation and cost of operations.

Net finance cost increased by 14% to N3.7 billion in 2024 from N3.2 billion in 2023 due to a slightly higher interest rate review in line with MPR.

Profit before tax from ordinary business of the Group  surged by 1110%, amounting to N34.7 billion in Q1 2024, compared to N2.9 billion in Q1 2023 in the same period last year.

Profit before tax inclusive of extra ordinary income was N45.7 billion in 2024 compared to N2.9 billion in 2023.

The Group recorded extra ordinary income of N11 billion during the period from the realised gain from the sale of shares.

Profit after Tax including the extra ordinary income improved 1832% year-on-year to N35.9 billion in Q1 2024, compared to N1.9 billion in Q1 2023 in the same period last year.

Earnings per share of the Group was N61.12k in Q1 2024, compared to N2.58k in Q1 2023.

On the balance sheet, total assets grew by 8.3%, from N530 billion in December 2023 to N574 billion in Q1 2024 due to the increase in operational activities.

Shareholders’ funds increased by 20% from N187billion in December 2023 to N224 billion at the end of Q1 2024 due to profit accreted to retained earnings.

In response to the results, Dr. Owen D. Omogiafo, president/group chief executive officer of Transcorp, commented, “Our Q1 2024 results demonstrates Transcorp Group’s resilience and commitment to excellence. Despite the challenges, we achieved growth across all major indices, focusing on operational efficiency at both our power plants, and maximising opportunities within our hospitality business, showing our ability to adapt and succeed in changing markets. We will continue to deliver sustainable growth, operational efficiency, and value for our shareholders.”

This robust achievement is a further demonstration of the Group’s strategic focus and effective execution.

Transcorp is dedicated to its transformation agenda, emphasising sustained growth and a relentless pursuit of long-term value for shareholders.

 

 

 


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