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Blood of Survivors Key to Ebola Virus Cure-WHO

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The best chance for an immediate treatment for Ebola patients in the worst outbreak in history may be readily available – in the blood of survivors.

With experimental drugs in short supply or not ready for use, global health officials are exploring whether the natural immunity survivors gain after they shed the virus can be shared with others.

The idea would be to use their plasma, the part of blood that contains antibodies, to help fight off the infection.

Some early research suggests using blood from survivors could be a success. In 1995 in Kikwit in the Democratic Republic of Congo, seven of eight infected people given the therapy survived during an outbreak with an 80 per cent fatality rate.

While studies have since showed conflicting results, the strategy is worth trying again as the current death toll rises, said David Wood, who leads a World Health Organisation team evaluating the approach.

It is “a feasible option”, said Mr Wood. “We’re consulting with the blood operators who have capability to assist, so that we can get some realistic sense of when this could be available as an option. We’ll have that information pretty soon.”

The WHO reported that by 13 August, 1,145 people had died from Ebola in Guinea, Sierra Leone, Liberia and Nigeria since the outbreak began.

The virus causes bleeding from the eyes, ears and nose with most patients dying from multiple organ failure.

About 40 per cent of people infected in the current outbreak have survived, according to the WHO. Researchers are targeting those who lived for a treatment that may not require drugmakers to be involved at all. Once the researchers get the blood, they will test it for other diseases and then separate out the plasma.

Antibodies in plasma are produced by white blood cells in response to foreign invaders in the body. They bind to the microbes, either neutralising them or flagging them for other parts of the immune system to attack.

Mary Kate Hart, an immunology researcher who did early studies of Ebola antibodies for the US Army, said that transfusions from survivors may carry a benefit, especially if given early in the course of the disease, and are likely to be relatively safe.

“It is not a crazy idea to try,” said Ms Hart, who is no longer involved in the antibody research. Kent Brantly, the American aid worker infected with Ebola in Liberia last month, was given such a treatment.

Mr Brantly received a blood transfusion from a 14-year-old survivor, according to Samaritan’s Purse, a North Carolina-based aid group. He also received an experimental antibody-based therapy.

While his condition has improved, it is not known if either the blood transfusion or the treatment, called “ZMapp”, aided his recovery, or whether his immune system fought off the virus.

“This would be something that countries could try themselves, and it would be much more feasible and much more immediate,” David Heymann, a professor of infectious diseases at the London School of Hygiene and Tropical Medicine, said of the transfusion treatment.

“But it shouldn’t take precedence over outbreak containment.”


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Verra Certifies d.light’s Clean Cookstove Projects in Sub-Saharan Africa

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A series of pioneering projects by d.light, the global provider of transformational household products and affordable finance for low-income households, to distribute 600,000 energy-efficient clean cookstoves in Kenya, Nigeria, and Uganda have been officially certified by global verification body Verra.

This certification confirms the d.light projects as trusted, verified sources of high-quality carbon credits in the voluntary carbon markets (VCMs).

The d.light projects aim to simultaneously reduce carbon emissions, tackle indoor air pollution, and reduce deforestation through the sale of highly efficient biomass cookstoves subsidized by the revenues from the sale of carbon credits.

Since their launch in late 2022, the projects have positively impacted more than one million lives and are projected to transform more than three million lives by 2025.

Commenting on the news, Karl Skare, d.light’s Chief Product and Strategy Officer, emphasized the projects’ positive impact, “With these projects, we’re not just addressing environmental concerns but also enhancing quality of life for millions.

“Each project underscores d.light’s commitment to practical, innovative solutions that address both environmental and social challenges, as part of our mission to transform the lives of one billion people by 2030.”

Each year, domestic cooking emissions contribute more than two percent of total global GHG emissions and up to 25 percent of anthropogenic black carbon emissions.

Highly energy-efficient cookstoves solve this problem by reducing biomass use by up to 70 percent compared to traditional cooking methods, cutting emissions of both carbon dioxide and black carbon.

The d.light projects are expected to reduce emissions by up to 12 million tons, contributing to climate change mitigation. These emissions reductions will be registered as carbon credits in the voluntary carbon market.

As well as reducing emissions, clean cookstoves are also a benefit to public health. According to the World Health Organisation, exposure to smoke from cooking fires causes an estimated 3.2 million premature deaths worldwide each year and is still one of the predominant causes of pollution-related illness and death in Africa.

In Uganda, for example, less than one percent of the population has access to clean cooking, household air pollution is the one of the largest risk factors for death and disability.

In addition, switching from traditional three-stone open fires to cleaner, energy-efficient cookstoves significantly reduces deforestation and reduces threats to wildlife and biodiversity caused by habitat loss.

Skare explained, “By subsidizing energy-efficient cookstove costs through carbon financing, d.light makes clean cooking accessible to more households, which in turn leads to healthier living conditions and conserves natural resources as well.

“Our projects in Kenya, Nigeria and Uganda are models of how sustainable investments can yield multiple co-benefits, aligning with global efforts to combat climate change and also promoting socio-economic development.

Skare added, “d.light now has projects certified by both Gold Standard and Verra, the world’s two leading certifiers of carbon credits. Organizations looking for ways to offset their own emissions can be confident that when they purchase carbon credits in d.light’s clean cooking projects in sub-Saharan Africa, they are investing in transformative initiatives that reduce harmful emissions, improve people’s health and quality of life, and help conserve the environment as well.”

 


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Remedial Health Unveils New App with Digital POS to power operations for Africa’s Neighbourhood Pharmacies

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Remedial Health, a health tech startup that develops solutions to make Africa’s pharmaceutical value chain more efficient has unveiled an updated version of its customer-facing app, designed to function as an operating system for neighbourhood pharmacies and Proprietary Patent Medicine Vendors (PPMVs) across the continent.

The new app comes with a digital POS terminal to support payment collection, virtual business accounts to receive payments, an in-built barcode scanner feature for recording product sales and store-switch functionality to enable the seamless management of multiple stores, as well as inventory management solutions for restocking and easily identifying short-dated products.

The app also offers comprehensive financial reporting to manage profit and loss, and data analytics to inform decision making.

Despite accounting for 85 per cent of retail medicines sold in Africa’s pharmaceutical industry (projected to reach $70 billion market size by 2030), the absence of bespoke digital tools to manage their unique sales and inventory management needs means neighbourhood pharmacies and Proprietary patent Medicine Vendors (PPMVs) are unable to run their operations as effectively and profitably as possible.

At the same time, the reliance on paper-based inventory and sales management processes means manufacturers have limited empirical insights into customer behaviour to inform their decisions on production and distribution.

The new Remedial Health app has been designed specifically for healthcare businesses in Africa, with tailored features that have been designed to support effective decision making to drive business growth and profitability.

Starting in Nigeria, healthcare businesses can access vetted medicines, and manage their sales and inventory on one easy-to-use platform, freeing up time and capacity to effectively serve their customers and communities.

The app also enables Remedial Health to provide consolidated, real-time data on market behaviour to manufacturers for increased profitability and better decision-making across the value chain.

According to Samuel Okwuada, CEO, and co-founder of Remedial Health, “Neighbourhood pharmacies and PPMVs represent the frontline of healthcare delivery in Africa but they have historically been left to their own devices to figure out how to be efficient and profitable.

“Our mission is to empower these essential service providers with the tools they need to manage day-to-day operations and seamlessly run their practices effectively. We spent a lot of time interacting with our customers in the process of delivering this product and the feedback has been great.

“We are excited by the opportunity to get the app into the hands of pharmacies and PPMVs across the country to support their ongoing success, as well as the health and wellbeing of the nation”.

In 2023, Remedial Health sold more than 300 million individual packs of medicines to 7,500 hospitals, neighbourhood pharmacies and PPMVs across all 36 states of Nigeria.

Its customers also improved their profits by 30 per cent on average, with access to more than 8,000 vetted products at the same, or better than, open-air medicine market prices.

They can also access same-day delivery and leverage inventory financing to minimise cash-flow friction for routine orders and maximise sales opportunities.


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EnterpriseNGR Expands Financial Centres to Three African Countries

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EnterpriseNGR has signed a Memorandum of Understanding to set up the Africa Roundtable of Financial Centres – a chapter of the World Alliance of International Financial Centres, in Mauritius, Morocco and Rwanda.

The MoU, signed recently in Mauritius, brought together EnterpriseNGR, the Economic Development Board of Mauritius, Casablanca Finance City Authority, and Rwanda Finance Limited to foster collaboration, promote investment opportunities, and drive sustainable development within the financial centres of its member countries and Africa at large.ort the exchange of best practices between members, enhance visibility regionally

A statement from EnterpriseNGR said that it was joining forces with the three countries to specifically pursue five key objectives.

These objectives include “Jointly strengthen the competitiveness of financial centres in Africa. Collaborate through projects, research papers, communiques, and events to position the African Continent, demonstrate the myriad of investment opportunities, and showcase the role that financial centres play within the African Continent.

“Conduct joint initiatives to supp and internationally, and provide African financial centres with a unified voice regionally and internationally.

“Facilitate the development of dialogue with major financial centres outside the African Continent and build communication channels with African institutions, including regulators and policymakers, as well as African financial services industry associations, and advocate for regulatory coordination amongst members of the Africa Roundtable to promote cross-border investments and financial services.”

Commenting on this collaboration, the Chairperson of the Africa Roundtable, Mr Ken Poonoosamy, said, “The signing of the Memorandum of Understanding for the Africa Roundtable of the WAIFC represents a pivotal stride in fostering synergy among financial hubs within the African sphere, with the shared objective of catalysing economic advancement across the continent.”

Ms Obi Ibekwe, the Chief Executive Officer of EnterpriseNGR, represented by the Director of Policy & Public Affairs, Mr Lami Adekola, expressed her excitement over the development.

She said, “It is a historic achievement, and EnterpriseNGR fully endorses the Africa Roundtable of the WAIFC and is excited for the immense opportunities it represents for Nigeria and the African continent. Our collaboration with the four African countries promises to bolster financial competitiveness on the Continent and amplify Africa’s global presence.

We will leverage this Roundtable to unlock the full potential of African financial centres to drive prosperity and development for our nations and beyond.”

EnterpriseNGR became a member of WAIFC in 2023 during the WAIFC board meeting hosted by TheCityUK in London.

The MoU, which was signed recently in Mauritius, brought together EnterpriseNGR, the Economic Development Board of Mauritius, Casablanca Finance City Authority, and Rwanda Finance Limited, to foster collaboration, promote investment opportunities, and drive sustainable development within the financial centres of its member countries.

A statement from EnterpriseNGR said that it was joining forces with the three countries to pursue five key objectives.

According to the group, these objectives include “jointly strengthen the competitiveness of financial centres in Africa. Collaborate through projects, research papers, communiques, and events to position the African continent, demonstrate the myriad of investment opportunities, and showcase the role that financial centres play within the African continent”.

It added that it would enable it to “Conduct joint initiatives to support the exchange of best practices between members, enhance visibility regionally and internationally, and to provide African financial centres with a unified voice regionally and internationally.

Facilitate the development of dialogue with major financial centres outside the African Continent and build communication channels with African institutions, including regulators and policymakers, as well as African financial services industry associations, and advocate for regulatory coordination amongst members of the Africa Roundtable to promote cross-border investments and financial services”.

Commenting on the collaboration, the Chairperson of the Africa Roundtable, Mr Ken Poonoosamy, asserted, “The signing of the Memorandum of Understanding for the Africa Roundtable of the WAIFC represents a pivotal stride in fostering synergy among financial hubs within the African sphere, with the shared objective of catalysing economic advancement across the continent.”

Ms Obi Ibekwe, the Chief Executive Officer of EnterpriseNGR, represented by the Director of Policy & Public Affairs, Mr Lami Adekola, expressed her excitement over the development.

She stated, “It is a historic achievement, and EnterpriseNGR fully endorses the Africa Roundtable of the WAIFC and is excited for the immense opportunities it represents for Nigeria and the African continent.

“Our collaboration with the four African countries promises to bolster financial competitiveness on the Continent and amplify Africa’s global presence. We will leverage this Roundtable to unlock the full potential of African financial centres to drive prosperity and development for our nations and beyond.”


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