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Blood Test Could Predict Parkinson’s 7 Years before Symptoms – AI Test

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A simple blood test could predict Parkinson’s disease seven years before symptoms appear, marking a “major step forward” in diagnosis of the condition.

Blood Test Could Predict Parkinson’s 7 Years before Symptoms – AI Test

Researchers believe early prediction and diagnosis would help in finding treatments that could slow or stop Parkinson’s.

Parkinson’s disease is a progressive disorder that affects the nervous system and the parts of the body controlled by the nerves.

The test uses artificial intelligence (AI) to predict the disease, which is caused by the death of nerve cells in the part of the brain that controls movement.

When these nerve cells die or become impaired, they lose the ability to create a chemical called dopamine.

People with Parkinson’s are currently treated with dopamine replacement therapy after they have already developed symptoms, such as tremors or slowness of movement.

It is thought that early diagnosis and treatment would help protect the dopamine-producing brain cells.

Dr Michael Bartl, co-first-author of University Medical Centre Goettingen and Paracelsus-Elena-Klinik Kassel, alongside Dr Jenny Hallqvist, UCL Queen Square Institute of Neurology, said: “By determining eight proteins in the blood, we can identify potential Parkinson’s patients several years in advance.

“This means that drug therapies could potentially be given at an earlier stage, which could possibly slow down disease progression or even prevent it from occurring.”

Professor David Dexter, director of research at Parkinson’s UK, said: “This research, co-funded by Parkinson’s UK, represents a major step forward in the search for a definitive and patient-friendly diagnostic test for Parkinson’s.

“Finding biological markers that can be identified and measured in the blood is much less invasive than a lumbar puncture, which is being used more and more in clinical research.”

The research found that when a branch of AI called machine learning analysed a panel of eight blood-based biomarkers whose concentrations are altered in patients with Parkinson’s, it could provide a diagnosis with 100% accuracy.

Professor Kevin Mills, senior author of UCL Great Ormond Street Institute of Child Health, said: “As new therapies become available to treat Parkinson’s, we need to diagnose patients before they have developed the symptoms.

“We cannot regrow our brain cells and therefore we need to protect those that we have.

“At present we are shutting the stable door after the horse has bolted and we need to start experimental treatments before patients develop symptoms.”

He added that with sufficient funding, it is hoped the test will be used by the NHS within two years.

The experts suggest that with further research this test could potentially distinguish between Parkinson’s and other conditions that have some early similarities.

The team also looked at whether the test could predict the likelihood of someone going on to develop Parkinson’s.

Blood from 72 patients with Rapid Eye Movement Behaviour Disorder (iRBD) was analysed as it is known that about 75% to 80% of these people will go on to develop a synucleinopathy – a type of brain disorder caused by the abnormal build-up of a protein called alpha-synuclein in brain cells – including Parkinson’s.

The patients were followed up over 10 years and researchers say the AI predictions have so far been correct, with the team correctly predicting 16 patients would go on to develop Parkinson’s and being able to do this up to seven years before the onset of any symptoms.

According to Parkinson’s UK, around one in 37 people alive today in the UK will be diagnosed with Parkinson’s in their lifetime, and there are 153,000 people already living with the condition.

The researchers are hoping to secure funding to create a simpler test where a drop of blood can be spotted on a card and posted to the lab to investigate if it can predict Parkinson’s even earlier than the seven years before the onset of symptoms in this study.

The research, which was funded by an EU Horizon 2020 grant, Parkinson’s UK, the National Institute for Health and Care Research GOSH Biomedical Research Centre, and the Szeben-Peto Foundation, is published in Nature Communications.

 

 

 


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Africa Fintech Revenues to Hit $65 billion by 2030 – Report

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African fintech revenues are projected to expand 13-fold to approximately $65 billion by 2030, marking the continent as the world’s fastest-growing digital finance market.

The “Beyond Payments: Unlocking Africa’s Second FinTech Wave ” report, released by Boston Consulting Group at the Inclusive FinTech Forum in Kigali, indicates the sector is shifting from transactional inclusion to scalable, infrastructure-driven systems.

While Sub-Saharan Africa accounts for 74% of global mobile money volume, more than 50% of lending still occurs through informal channels, representing a massive gap for B2B payments and data-driven underwriting.

The opportunity now is to convert scale into sustained, institutional-grade growth, says the report. Markets offering regulatory clarity and interoperable infrastructure are becoming increasingly attractive to long-term capital.

Rwanda is highlighted as an example of deliberate institutional coordination that lowers the cost to scale for financial institutions.

Forward-looking regulation and the License Passporting Memorandum of Understanding between Rwanda and Kenya are cited as practical steps toward easing regional expansion.

Financial centres like the Kigali International Financial Centre play a critical role in this next phase by reducing uncertainty for banks and investors.

By combining regulatory clarity and Pan-African integration, they reduce uncertainty for banks, fintechs, and investors, and help position markets as credible, long-term investment destinations.

Africa’s next fintech phase will be led by financial institutions, the report notes. It goes on to say banks and regulated entities are becoming the primary customers of digital financial infrastructure, demanding platforms that align with their risk frameworks.

The report identifies five institutional priorities to sustain momentum: interoperable infrastructure, data-driven credit, regulatory coherence, trust, and resilience.

Building seamless wallet-to-bank integration will enable more efficient value movement, while transforming transaction data into AI-enabled underwriting models will help bridge the gap in SME lending.

Proportional licensing frameworks and predictable supervisory practices will lower the cost to scale for innovators. Furthermore, expanding cybersecurity capabilities will ensure the ecosystem remains reliable as digital usage grows.

Africa has demonstrated that fintech scale is achievable, and the next decade will be shaped by those markets that strengthen their institutional foundations, the report concludes.

 


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This Is Nigeria Launches ‘The 36: Nigeria Unscripted’ to Showcase Nation’s Culture, Innovation

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For too long, the story of Nigeria has been told by foreigners or shaped by people who don’t truly understand our spirit; This Is Nigeria is a movement changing that. We are putting the power back into the hands of Nigerians to tell our stories from our perspectives.

This Is Nigeria Launches ‘The 36: Nigeria Unscripted’ to Showcase Nation’s Culture, Innovation

Our mission is simple: to change how the world sees us by sharing the positive, impactful stories of our land and its people.

Today, we are officially launching “The 36: Nigeria Unscripted”. This series will travel through every single state in the country, starting with our pilot season in Lagos. We want to show the world the true drive, food, diversity, culture, and innovation that define Nigerians at home.

“The 36: Nigeria Unscripted” takes a deep dive into the history, people, landmarks, and investment potential that make each state unique. Instead of focusing on the usual headlines, we are highlighting the real people building businesses, creating new technologies, making scientific breakthroughs, and leading cultural shifts here and across the globe.

The Kick-Off

The journey begins in Lagos. Over the next two weeks, our crew will be on the streets filming the vibrant energy of the city. This is a “boots-on-the-ground” look at what Nigerian innovation actually looks like today.

Alongside the series, we are also launching a Global Desk. This is a dedicated space to find and share stories of Nigerians living abroad who are making us proud with that signature Nigerian excellence.

How We Are Different

Most Nigerian travel content usually falls into two categories: it’s either a refined ad that ignores reality, or it focuses only on struggle while ignoring achievements.

This Is Nigeria rejects both. Our campaign gives you a behind-the-scenes look at the real passion and effort that fuel our success.

For more information or to share your story, visit www.thisis-nigeria.com.


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Court Orders SERAP to Pay DSS Operatives N100m Damages Over Defamation

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Federal Capital Territory (FCT) High Court in Abuja has ordered the Incorporated Trustees of the Socio-Economic Rights and Accountability Project (SERAP) to pay N100 million in damages to two operatives of the Department of State Services (DSS) over defamation.

Court Orders SERAP to Pay DSS Operatives N100m Damages Over Defamation

SERAP

Justice Yusuf Halilu delivered the judgment in a suit filed by two DSS operatives, Sarah John and Gabriel Ogundele, who accused SERAP of making false and defamatory claims against them.

The claimants had approached the court following a series of posts published by SERAP on its X handle on Sept. 9, 2024, alleging that DSS officers unlawfully invaded and occupied its Abuja office.

In the posts, SERAP claimed that officers of the State Security Service had stormed its office and were demanding to see its directors.

“Officers from Nigeria’s State Security Service are presently unlawfully occupying SERAP’s office in Abuja, asking to see our directors. President Tinubu must immediately direct the SSS to end the harassment, intimidation, and attack on the rights of Nigerians,” the organisation had posted.

However, in his judgment, Justice Halilu held that the allegations made by SERAP were false and defamatory, adding that the two DSS operatives were justified in instituting legal action to protect their reputations.

The court consequently awarded N100 million in damages against SERAP in favour of the claimants.

Justice Halilu also ordered SERAP to issue a public apology to the two DSS operatives.

According to the judgment, the apology must be published in two national newspapers and aired on two television stations.

In addition, the court awarded N1 million against SERAP as the cost of litigation.

The court further ruled that the judgment sum would attract 10 per cent interest annually until the full amount is paid.

The case stems from growing tensions between civil society organisations and security agencies over allegations of harassment, intimidation, and civic space restrictions in Nigeria.

Neither SERAP nor the DSS had publicly reacted to the judgment as of the time of filing this report.


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